Unit 1 - Essential Haematology and Transfusion

Indicative Content
In this Unit, you will learn about:

• Red cell physiology 
  
• Haemostasis and platelet physiology
  
• Pathology of anaemia and haematological diseases (overview)
  
• Management of blood components in the hospital: Part 1 (standard routine practices)
  
• Epidemiology of blood transfusion
  
• Adverse effects of transfusion – Part 1 (overview)
  

Learning Outcomes
You will be expected to:

1. Outline, describe, determine, explain and classify the key features of red cell physiology with respect to the bone marrow, erythropoietin and red cell production, iron composition, function, contents, lifespan, and senescent destruction
   
   
2. Describe, explain and classify the vascular system with respect to the arteries, capillaries, veins, lymphatics and cardiac output, distribution of blood volume, flow and blood pressure control
   
   
3. Describe, explain and categorise the key features of haemostasis and platelet physiology with respect to platelet production, lifespan, function, use of antiplatelet agents, the coagulation proteins/cascade including use of anticoagulant agents (heparin/ warfarin/ DOACs)
   
   
4. Describe, explain and categorise point-of-care viscoelastic tests of coagulation
   
   
5. Describe, explain and categorise basic haematology laboratory tests with respect to blood cell counts and blood cell morphology
   
   
6. Describe, explain and classify the pathology of anaemia and a range of haematological diseases including haemoglobinopathies and thalassaemias, leukaemias and lymphomas, aplastic anaemia and haemostatic disorders 
   
   
7. Describe, categorise and explain the management of blood components in the hospital setting with respect to transfusion laboratory storage and their transport and temperature control outside the transfusion laboratory
   
   
8. Describe, categorise and explain the administration of different component types, from prescription to completion of the transfusion episode
   
   
9. Describe, explain, interpret and predict the epidemiology of blood transfusion with respect to blood use in the UK. Compare and contrast the UK with international practices
   
   
10. Determine, explain, classify, demonstrate and predict the adverse effects associated with various aspects of blood transfusion with respect to non-infectious and infectious types; including mechanics, cause, recognition of signs and symptoms. Justify reactive, proactive and preventative measures to avoid known types and emerging infections
    

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Unit 2 - Transfusion Therapy