Red Cell Mechanics and Function

Special Interest Group 1 of 3

Day: Wednesday  |   Time: 10:30 - 12:00  |  Room: Auditorium

Session Coordinators: 
Lesley Bruce & Vanja Crew

Presentations: 

Effects of red cell shape and cytoplasmic tortuosity on oxygen transport, measured by single-cell oxygen-saturation imaging
Pawel Swietach, University of Oxford

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Red blood cell tension controls Plasmodium falciparum invasion and protects against severe malaria in the Dantu blood group
Viola Introini, University of Cambridge

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Dielectric characterization of Plasmodium falciparum-infected red blood cells using microfluidic impedance cytometry
Daniel Spencer, University of Southampton

Presentation Unavailable

Brief Description
The first session of this year’s Red Cell SIG will be focused on novel research in the field of red cell mechanics and function. The participants will be able to learn about the effects of red cell shape on oxygen transport, followed by two talks familiarising the audience with the effects of malaria infection on red cell membranes and red cell biophysics.

Intended Audience
This Red Cell SIG session should be of interest to biomedical scientists and trainees working in hospital transfusion departments; UK Blood Services and associated services; research scientists involved in red cell and/or basic research work; clinicians who prescribe blood components in haematology, surgery, intensive care, obstetrics and trauma settings; transfusion practitioners; anyone in the wider scientific community who is interested in the current red cell research carried out in the UK.

Learning Objectives

1) Learning about the effects of red cell shape on oxygen transport through evaluation of CO2 diffusivity